Professor Chang’s study, funded with more than £400,000 from the Biotechnology and Biological Sciences Research Council, will focus on the differences between fast muscle fibres and slow muscle fibres.

Slow muscle fibres, otherwise known as oxidative or red muscle, is associated with the most sought-after qualities of meat such as flavour intensity or tenderness whereas meat from fast muscle fibres, which tend to be bulkier and grow more rapidly, is considered to be tougher and drier.

Packed with capillaries, mitochondria and myoglobin that give the meat its darker colour, slow muscle fibres are more efficient at converting sugar and fatty acids to energy and, although slower to contract, will therefore function for longer before tiring. These are usually associated with animals that are living free range and are on the move for longer and produce flavoursome meat.

Farmers and consumers are currently faced with the problem that breeds chosen because they can grow quicker and produce larger quantities of meat and are therefore economically more attractive tend to predominantly produce fast muscle.

Professor Chang said: “Genetically, we have been very successful in breeding animals that can grow very quickly but the down side is that comes at the price of eating quality.

“The work we are doing focuses on finding out more at a molecular level about how fast muscle can switch to slow muscle and could lead to a better understanding of how to genetically choose animals for breeding that will produce better quality meat.”

The issue of fast and slow muscle affects all meat but is particularly pertinent to pork, chicken, lamb and beef in which animals are chosen for breeding according to how fast they grow and how much meat each animal can produce.

For example, in poultry farming broiler chickens take just six weeks to grow from hatching to slaughter and grow much faster than hens produced for egg production. However, the breast meat produced is often criticised as being bland in flavour.

The lab-based science being conducted at Nottingham is concentrating on a particular cell signalling pathway called the calcineuring pathway which, if stimulated, causes muscle to switch from fast to slow.

Learning more about this process could lead to the identification of genes important in the growth of slow muscle and allow farmers to use the wealth of genetic diversity that exists in animals to breed naturally tastier and succulent meat.

Part of the funding for the project will come from the pharmaceutical company Pfizer as an industrial partnership, reflecting the potential that the project may have in the development of new pharmacological products to safely target the growth of slow muscle in existing meat-producing breeds.

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Notes to editors: The University of Nottingham is ranked in the UK's Top 10 and the World's Top 70 universities by the Shanghai Jiao Tong (SJTU) and Times Higher (THE) World University Rankings.


It provides innovative and top quality teaching, undertakes world-changing research, and attracts talented staff and students from 150 nations. Described by The Times as Britain's "only truly global university", it has invested continuously in award-winning campuses in the United Kingdom, China and Malaysia. Twice since 2003 its research and teaching academics have won Nobel Prizes. The University has won the Queen's Award for Enterprise in both 2006 (International Trade) and 2007 (Innovation — School of Pharmacy).
 
Its students are much in demand from 'blue-chip' employers. Winners of Students in Free Enterprise for four years in succession, and current holder of UK Graduate of the Year, they are accomplished artists, scientists, engineers, entrepreneurs, innovators and fundraisers. Nottingham graduates consistently excel in business, the media, the arts and sport. Undergraduate and postgraduate degree completion rates are amongst the highest in the United Kingdom.